It doesn't matter if you have any DLCs or not. The 1.8 patch was big enough to break any mod that adds races at least.
Hopefully Jason will notice the update soon. From what I can tell this won't be as much work as the 1.5 update.
Here is a mini-mod that fixes the main issues.
In developer mode there are still some minor popup errors which I'll track down hopefully this afternoon.
Add this as the top-most mod in the list, above Requiem 4 and Requiem Resources
I just fixed some errors with the 1.80 hotfix file.
(Jason: I removed this link... the slow download link is invalid and the fast download asks for a credit card: not cool).
That is probably Sins hitting its 2GB RAM limit. With large Sins mods you must reduce your texture quality (planet, ship, structure detail) settings to avoid hitting this limit. Very few PCs can run Sins mods on all highest settings.